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Selitrectinib (Standard)

CAT: 0804-HY-101977R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101977R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selitrectinib (Standard) is the analytical standard of Selitrectinib. This product is intended for research and analytical applications. Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and TRKA and TRKC, respectively[1].
CAS Number
2097002-61-2
Product Name Alternative
LOXO-195 (Standard)
UNSPSC
12352005
Target
Reference Standards; Trk Receptor
Type
Reference Standards
Related Pathways
Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/selitrectinib-standard.html
Smiles
FC1=CN=C(CC[C@H](N2)C)C([C@](CCC3)([H])N3C(C=CN4N=C5)=NC4=C5C2=O)=C1
Molecular Formula
C20H21FN6O
Molecular Weight
380.42
References & Citations
[1]Drilon A, et al. A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors. Cancer Discov. 2017 Sep;7 (9) :963-972.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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