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Derazantinib

CAT: 0957-S8609-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0957-S8609-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Derazantinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM) . It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
CAS Number
1234356-69-4
Synonyms
ARQ-087
Target
FGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C29H29FN4O
Storage Conditions
3 years -20°C powder

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