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EED226

CAT: 0957-S8496-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S8496-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EED226 is a potent, selective, and orally bioavailable a novel allosteric Polycomb repressive complex 2 (PRC2) inhibitor with an IC50 of 23.4 nM when the H3K27me0 peptide was used as substrate and an IC50 of 53.5 nM when the mononucleosome was used as the substrate. It directly binds to the H3K27me3 binding pocket of EED.
CAS Number
2083627-02-3
Target
Epigenetic Reader Domain
Activity
Epigenetics
Molecular Formula
C17H15N5O3S
Storage Conditions
2 years -80 in solvent

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