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Picropodophyllin (PPP)

CAT: 0957-S7668-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7668-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR (FGF-R, PDGF-R, OR EGF-R) . Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.
CAS Number
477-47-4
Synonyms
AXL1717
Target
IGF-1R
Activity
Protein Tyrosine Kinase
Molecular Formula
C22H22O8
Storage Conditions
2 years -80 in solvent

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