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Poziotinib

CAT: 0957-S7358-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7358-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Poziotinib is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Poziotinib also induces apoptosis and G1 cell cycle arrest. Phase 2.
CAS Number
1092364-38-9
Synonyms
HM781-36B, NOV120101
Target
HER2
Activity
Protein Tyrosine Kinase
Molecular Formula
C23H21Cl2FN4O3
Storage Conditions
2 years -80 in solvent