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Binimetinib (MEK162)

CAT: 0957-S7007-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S7007-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3.
CAS Number
606143-89-9
Synonyms
ARRY-162, ARRY-438162
Target
MEK
Activity
Protein Tyrosine Kinase
Molecular Formula
C17H15BrF2N4O3
Storage Conditions
2 years -80 in solvent