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SIS3

CAT: 0957-S3552-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S3552-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SIS3 is a cell-permeable inhibitor of Smad3 that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. SIS3 reduces TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
CAS Number
1009104-85-1
Target
TGF-beta/Smad
Activity
TGF-beta/Smad
Molecular Formula
C28H27N3O3
Storage Conditions
3 years -20°C powder

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