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Tofacitinib

CAT: 0957-S2789-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2789-01Size:5 mg
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Description
Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.
CAS Number
477600-75-2
Synonyms
CP-690550, Tasocitinib
Target
JAK
Activity
Angiogenesis
Molecular Formula
C16H20N6O
Storage Conditions
2 years -80 in solvent

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