RPSA Polyclonal Antibody

• Background:

  Required for the assembly and/or stability of the 4S ribosomal subunit. Required for the processing of the 2S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 4S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.

• Synonyms:

  SA; LBP; LRP; p4; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p4; NEM/1CHD4; 4S ribosomal protein SA; 37 kDa laminin receptor precursor; 37/67 kDa laminin receptor; 67 kDa laminin receptor; Colon carcinoma laminin-binding protein; Laminin receptor 1; Laminin-binding protein precursor p4; Multidrug resistance-associated protein MGr1-Ag; RPSA

• Gene ID:

  3921

• Swiss Prot:

  P08865

• Cellular Locus:

  Cytoplasm, Nucleus, Cell membrane, Extracellular matrix

• Host:

  Rabbit

• Cross Reactivity:

  Mouse, Rat

• Immunogen:

  201-295/295

• Target:

  RPSA

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human LAMR1

• Applications:

  WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  3921

• Predicted Cross Reactivity:

  Human, Dog