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Xevinapant (AT406)

CAT: 0957-S2754-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2754-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Xevinapant (AT406, ARRY-334543, Debio1143, SM-406) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
CAS Number
1071992-99-8
Synonyms
ARRY-334543, Debio1143, SM-406
Target
E3 Ligase
Activity
Ubiquitin
Molecular Formula
C32H43N5O4
Storage Conditions
2 years -80 in solvent

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A11163-500Xevinapant (AT-406, SM-406, ARRY-334543) 500mg
A11163-25Xevinapant (AT-406, SM-406, ARRY-334543) 25mg
A11163-2Xevinapant (AT-406, SM-406, ARRY-334543) 2mg
A11163-100Xevinapant (AT-406, SM-406, ARRY-334543) 100mg

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