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Xevinapant hydrochloride

CAT: 0931-T3299Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T3299Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1071992-57-8
Target
IAP, Apoptosis
Related Pathways
Apoptosis
Bioactivity
Xevinapant hydrochloride (AT-406 HCl), an orally active antagonist of multiple inhibitor of apoptosis proteins (IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
Smiles
Cl.[H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)C(=O)CC(C)C)NC(=O)[C@H](C)NC)C(=O)NC(c1ccccc1)c1ccccc1
Molecular Formula
C32H44ClN5O4
Molecular Weight
598.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-13208-01Xevinapant (hydrochloride)
GTR19193625-01Xevinapant hydrochloride
HY-15454-01Xevinapant
C08831-25mgXevinapant (AT406)
A11163-500Xevinapant (AT-406, SM-406, ARRY-334543) 500mg
A11163-25Xevinapant (AT-406, SM-406, ARRY-334543) 25mg
A11163-2Xevinapant (AT-406, SM-406, ARRY-334543) 2mg
A11163-100Xevinapant (AT-406, SM-406, ARRY-334543) 100mg
A11163-1Xevinapant (AT-406, SM-406, ARRY-334543) 1mg
A11163-10mM-DXevinapant (AT-406, SM-406, ARRY-334543) 10mM * 1mL in DMSO

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