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PHA-767491 HCl

CAT: 0957-S2742-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S2742-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHA-767491 (CAY10572, NMS 1116354) HCl is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell-free assays, respectively.It displays ~20-fold selectivity against CDK1/2 and GSK3-β, 50-fold selectivity against MK2 and CDK5, 100-fold selectivity against PLK1 and CHK2.
CAS Number
942425-68-5
Synonyms
CAY10572, NMS 1116354
Target
CDK
Activity
Cell Cycle
Molecular Formula
C12H11N3O.HCl
Storage Conditions
2 years -80 in solvent

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