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Fedratinib (TG101348)

CAT: 0957-S2736-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2736-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.
CAS Number
936091-26-8
Synonyms
SAR302503
Target
JAK
Activity
Angiogenesis
Molecular Formula
C27H36N6O3S
Storage Conditions
2 years -80 in solvent

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