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Tolbutamide (HLS 831)

CAT: 0957-S2443-01Size: 50 mgDry Ice: YesHazardous: No
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Description
Tolbutamide (HLS 831) is an inhibitor of potassium channel, used for type II diabetes.
CAS Number
64-77-7
Target
Potassium Channel
Activity
Transmembrane Transporters
Molecular Formula
C12H18N2O3S
Storage Conditions
2 years -80 in solvent

Chemical Information

Tolbutamide

Tolbutamide is an N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position. It has a role as a hypoglycemic agent, a potassium channel blocker, a human metabolite and an insulin secretagogue.

CAS Number64-77-7
PubChem CID5505
IUPAC Name1-butyl-3-(4-methylphenyl)sulfonylurea
Molecular FormulaC12H18N2O3S
Molecular Weight270.35
XLogP2.3
Topological Polar Surface Area83.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Heavy Atom Count18
Formal Charge0
Complexity354
SMILES
CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C
InChI
InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)
InChIKey
JLRGJRBPOGGCBT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tolbutamide
CAS: 64-77-7
CID: 5505
Formula: C12H18N2O3S
MW: 270.35
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.35
XLogP32.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass270.10381361
Monoisotopic Mass270.10381361
Topological Polar Surface Area83.7 Ų
Heavy Atom Count18
Formal Charge0
Complexity354
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C08566-1gTolbutamide (HLS 831)
B2194-5.1Tolbutamide
B4957-5000Tolbutamide Sodium
FH24142-01Hydroxy tolbutamide
HY-B0401ATolbutamide (sodium)
HY-B0401S-01Tolbutamide-d9

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