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L-2-Hydroxyglutaric acid disodium

CAT: 0957-S1325-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S1325-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-2-Hydroxyglutaric acid disodium ((S) -2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively.
CAS Number
63512-50-5
Synonyms
(S) -2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG
Target
Histone Demethylase
Activity
Epigenetics
Molecular Formula
C5H6Na2O5
Storage Conditions
3 years -20°C powder

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