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Celastrol

CAT: 0957-S1290-03Size: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S1290-03Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy.
CAS Number
34157-83-0
Synonyms
NSC 70931, Tripterine
Target
Proteasome
Activity
Proteases
Molecular Formula
C29H38O4
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
200694Celastrol

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