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Foretinib

CAT: 0957-S1111-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1111-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Foretinib is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
CAS Number
849217-64-7
Synonyms
GSK1363089, EXEL-2880, XL-880, GSK089
Target
C-Met
Activity
Protein Tyrosine Kinase
Molecular Formula
C34H34F2N4O6
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
AR-F10770-01Foretinib

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