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LY294002

CAT: 0957-S1105-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S1105-01Size:10 mg
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Description
LY294002 (SF 1101, NSC 697286) is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. It not only binds to class I PI3Ks and other PI3K-related kinases, but also to novel targets seemingly unrelated to the PI3K family. LY294002 also inhibits CK2 with IC50 of 98 nM. LY294002 is a non-specific DNA-PKcs inhibitor and activates autophagy and apoptosis.
CAS Number
154447-36-6
Synonyms
SF 1101, NSC 697286
Target
Autophagy
Activity
Autophagy
Molecular Formula
C19H17NO3
Storage Conditions
2 years -80 in solvent

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CatalogName
HY-10108-01LY294002
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HY-10108A-01LY294002 (hydrochloride)
1747-5EZSolution™ LY294002
A10547-100LY294002 100mg
A10547-25LY294002 25mg

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