ACY-775

CAT: 0957-S0864-02Size: 10 mm/ 1 mLDry Ice: NoHazardous: No

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CAT#:0957-S0864-02Size:10 mm/ 1 mL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ACY-775 is a potent and selective histone deacetylase 6 (HDAC6) inhibitor with IC50 of 7.5 nM.

CAS Number

1375466-18-4

Target

HDAC

Activity

DNA Damage/DNA Repair

Molecular Formula

C17H19FN4O2

Storage Conditions

3 years -20°C powder

Chemical Information

2-((1-(3-fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide

CAS Number	1375466-18-4
PubChem CID	57382288
IUPAC Name	2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxypyrimidine-5-carboxamide
Molecular Formula	C17H19FN4O2
Molecular Weight	330.36
XLogP	2.5
Topological Polar Surface Area	87.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Heavy Atom Count	24
Formal Charge	0
Complexity	423

SMILES

C1CCC(CC1)(C2=CC(=CC=C2)F)NC3=NC=C(C=N3)C(=O)NO

InChI

InChI=1S/C17H19FN4O2/c18-14-6-4-5-13(9-14)17(7-2-1-3-8-17)21-16-19-10-12(11-20-16)15(23)22-24/h4-6,9-11,24H,1-3,7-8H2,(H,22,23)(H,19,20,21)

InChIKey

IYBURCQQEUNLDL-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1375466-18-4

CID: 57382288

Formula: C17H19FN4O2

MW: 330.36

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	330.36
XLogP3	2.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	330.14920402
Monoisotopic Mass	330.14920402
Topological Polar Surface Area	87.1 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	423
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes