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ACY-957

CAT: 0957-E7940-1mgSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-E7940-1mgSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1609389-52-7
Target
HDAC
Applications
DNA Damage/DNA Repair
Molecular Formula
C24H23N5OS
Additionnal Information
ACY-957 is a selective chemical inhibitor of HDAC1 and HDAC2 with an IC50 values of 7 nM, 18 nM against HDAC1/2 respectively. It induces hemoglobin protein (HbF) in primary erythroid progenitor cells, including those from sickle cell patients, offering a promising approach for treating sickle cell disease (SCD) and β-thalassemia.