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GEM144

CAT: 0957-E8292Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E8292Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GEM144 is a potent and orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC11 . It exhibits potent antiproliferative activity in vitro and antitumor efficacy in vivo by inducing p53 acetylation, p21 activation, G1/S cell cycle arrest, and apoptosis.
CAS Number
2487526-28-1
Synonyms
Flezurafenibum
Target
HDAC
Activity
DNA Damage/DNA Repair

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C04944GEM144
A24023-10GEM144 10mg
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