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HS-10296 hydrochloride

CAT: 0957-E4886-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E4886-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HS-10296 hydrochloride (Almonertinib (hydrochloride), HS-10296 HCl) is an irreversible, third-generation inhibitor of EGFR tyrosine kinase that demonstrates high selectivity for EGFR-sensitizing mutations, T790M resistance mutation. It exhibits inhibitory activity against T790M, T790M/L858R, and T790M/Del19, with IC50 of 0.37 nM, 0.29 nM, and 0.21 nM, respectively. It also exhibits anti-tumor activity.
CAS Number
2134096-03-8
Synonyms
Almonertinib (hydrochloride), HS-10296 HCl
Target
EGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C30H35N7O2.ClH

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Alternative Products

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MBS3846088-01HS-10296 hydrochloride
A21661-500Almonertinib hydrochloride (HS-10296 hydrochloride) 500mg
A21661-50Almonertinib hydrochloride (HS-10296 hydrochloride) 50mg
A21661-100Almonertinib hydrochloride (HS-10296 hydrochloride) 100mg
A21661-25Almonertinib hydrochloride (HS-10296 hydrochloride) 25mg
A21661-5Almonertinib hydrochloride (HS-10296 hydrochloride) 5mg
A21661-1Almonertinib hydrochloride (HS-10296 hydrochloride) 1mg
A21661-10Almonertinib hydrochloride (HS-10296 hydrochloride) 10mg
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