Bag1 Recombinant Antibody, PE Conjugated

• Background:

  Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

• Synonyms:

  BAG1; HAP1; RAP46.

• Gene ID:

  573

• Swiss Prot:

  Q99933

• Cellular Locus:

  Cytoplasm, Nucleus, Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  Bag1

• Clonality:

  Recombinant

• Conjugation:

  PE

• Source:

  KLH conjugated synthetic peptide derived from human BAG1

• Applications:

  WB, IF, Flow-Cyt

• Purification:

  Purified by Protein A.

• Excitation Emission:

  496,564nm/578nm

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  573

• Isotype:

  IgG