PHD3 Recombinant Antibody

• Background :

  Prolyl hydroxylase that mediates hydroxylation of proline residues in target proteins, such as PKM, TELO2, ATF4 and HIF1A.Target proteins are preferentially recognized via a LXXLAP motif. Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins.

• Synonyms :

  Egl nine homolog 3; EGLN3; Factor responsive smooth muscle protein; HIF Prolyl Hydroxylase 3; HIFP4H3; HIFPH3; P4H3; PHD3; SM20.

• Gene ID :

  112399

• Swiss Prot :

  Q9H6Z9

• Cellular Locus :

  Nucleus

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse, Rat

• Target :

  PHD3

• Clonality :

  Recombinant

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human PHD3

• Applications :

  WB, IP, ICC/IF

• Purification :

  Purified by Protein A.

• Concentration :

  Lot dependent

• Dilution :

  WB (1:300-5000), IP (1-2ug), ICC/IF (1:50-100)

• Buffer :

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  112399

• Isotype :

  IgG