Traumatic Acid

• Description :

  Traumatic Acid is a wound healing agent and a cytokinin (phytohormone) . Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis[1][2].

• Product Name Alternative :

  Rovamycin, Rovamycin (hexanedioate)

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H319

• Target :

  Apoptosis; Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/traumatic-acid.html

• Concentration :

  10mM

• Purity :

  99.27

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  O=C(O)/C=C/CCCCCCCCC(O)=O

• Molecular Formula :

  C12H20O4

• Molecular Weight :

  228.28

• Precautions :

  H315, H319

• References & Citations :

  [1]Jabłońska-Trypuć A, et al. Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts.Lipids. 2016 Sep;51 (9) :1021-35.|[2]Jabłońska-Trypuć A, et al. Traumatic acid toxicity mechanisms in human breast cancer MCF-7 cells. Regul Toxicol Pharmacol. 2019 Aug;106:137-146.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [6402-36-4]