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Traumatic Acid

CAT: 0804-HY-119358-01Size: 50 mgDry Ice: NoHazardous: No
CAT#: HY-119358-01Size: 50 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Traumatic Acid is a wound healing agent and a cytokinin (phytohormone) . Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis[1][2].
CAS Number
[6402-36-4]
Product Name Alternative
Rovamycin
,
Rovamycin (hexanedioate)
UNSPSC
12352211
Hazard Statement
H315, H319
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/traumatic-acid.html
Concentration
10mM
Purity
99.27
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C/CCCCCCCCC(O)=O
Molecular Formula
C12H20O4
Molecular Weight
228.28
Precautions
H315, H319
References & Citations
[1]Jabłońska-Trypuć A, et al. Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts.Lipids. 2016 Sep;51 (9) :1021-35.|[2]Jabłońska-Trypuć A, et al. Traumatic acid toxicity mechanisms in human breast cancer MCF-7 cells. Regul Toxicol Pharmacol. 2019 Aug;106:137-146.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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