CD207 Recombinant Antibody

• Background:

  Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs) ; is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur.

• Synonyms:

  CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CLEC4K; Langerhans cell specific c type lectin; Langerin.

• Gene ID:

  50489

• Swiss Prot:

  Q9UJ71

• Cellular Locus:

  Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  CD207

• Clonality:

  Recombinant

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human CD207

• Applications:

  IHC-P, IHC-F, IF

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  IHC-P (1:200-400), IHC-F (1:100-500), IF ()

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  50489

• Isotype:

  IgG