CD207 Recombinant Antibody

• Background :

  Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs) ; is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur.

• Synonyms :

  CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CLEC4K; Langerhans cell specific c type lectin; Langerin.

• Gene ID :

  50489

• Swiss Prot :

  Q9UJ71

• Cellular Locus :

  Cell membrane

• Host :

  Rabbit

• Cross Reactivity :

  Human

• Target :

  CD207

• Clonality :

  Recombinant

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human CD207

• Applications :

  IHC-P, IHC-F, IF

• Purification :

  Purified by Protein A.

• Concentration :

  Lot dependent

• Dilution :

  IHC-P (1:200-400), IHC-F (1:100-500), IF ()

• Buffer :

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  50489

• Isotype :

  IgG