CHD4 Recombinant Antibody

• Background:

  ATP-dependent helicase that binds and distorts nucleosomal DNA.Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:17626165, PubMed:28977666.Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination.

• Synonyms:

  ATP dependent helicase CHD4; CHD4; Chromodomain helicase DNA binding protein 4; Mi 2 autoantigen 218 kDa protein; Mi 2b; Mi2 beta.

• Gene ID:

  1108

• Swiss Prot:

  Q14839

• Cellular Locus:

  Cytoplasm, Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  CHD4

• Clonality:

  Recombinant

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human CHD4

• Applications:

  WB, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  1108

• Isotype:

  IgG