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CM272

CAT: 0957-S8812-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8812-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CM-272 is a novel first-in-class dual reversible inhibitor of G9a (GLP) and DNMTs with IC50 of 8 nM, 382 nM, 85 nM, 1200 nM, 2 nM for G9a, DNMT1, DNMT3A, DNMT3B, GLP, respectively. CM-272 prolongs survival in in vivo models of haematological malignancies by at least in part inducing immunogenic cell death.
CAS Number
1846570-31-7
Target
DNA Methyltransferase
Activity
Epigenetics
Molecular Formula
C28H38N4O3
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
C13688-10mM/1mLCM272

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