Products for Research Use Only
RegisterLogin

CM272

CAT: 1568-C13688-10mM/1mLSize: 10 mM/1mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C13688-10mM/1mLSize:10 mM/1mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1846570-31-7
Target
DNA Methyltransferase
Applications
Epigenetics
Smiles
CC1=CC=C (O1) C2=NC3=CC (=C (C=C3C (=C2) NC4CCN (CC4) C) OC) OCCCN5CCCC5
Molecular Formula
C28H38N4O3
Additionnal Information
CM-272 is a novel first-in-class dual reversible inhibitor of G9a (GLP) and DNMTs with IC50 of 8 nM, 382 nM, 85 nM, 1200 nM, 2 nM for G9a, DNMT1, DNMT3A, DNMT3B, GLP, respectively. CM-272 prolongs survival in in vivo models of haematological malignancies by at least in part inducing immunogenic cell death.
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
S8812-5mgCM272

Popular Products