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4-Methyl-2-oxovaleric acid

CAT: 0957-S2987-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0957-S2987-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Methyl-2-oxovaleric acid (Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate) is released by Astrocytes to neurons and can be reaminated by aminotransferase to leucine. 4-Methyl-2-oxovaleric acid reduces the rate of protein degradation in skeletal muscle. 4-Methyl-2-oxovaleric acid acts as an uncoupler of oxidative phosphorylation (OXPHOS) and as a metabolic inhibitor possibly through its inhibitory effect on alpha-ketoglutarate dehydrogenase (oxoglutarate dehydrogenase complex, OGDC) activity.
CAS Number
816-66-0
Synonyms
Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate
Target
OXPHOS
Activity
Apoptosis
Molecular Formula
C6H10O3
Storage Conditions
2 years -20°C liquid

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