IRAKM Recombinant Antibody

• Background:

  Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.

• Synonyms:

  ASRT5; FLJ13601; IL-1 receptor-associated kinase M; Interleukin-1 receptor-associated kinase 3; interleukin-1 receptor-associated kinase M; IRAK-3; IRAK-M; IRAK3; IRAKM.

• Gene ID:

  11213

• Swiss Prot:

  Q9Y616

• Cellular Locus:

  Cytoplasm

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  IRAKM

• Clonality:

  Recombinant

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human IRAK3

• Applications:

  WB, IP

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IP (1-2ug)

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  11213

• Isotype:

  IgG