Products for Research Use Only
RegisterLogin

ApoER2 Polyclonal Antibody

CAT: 0498-bs-6651R-TRSize: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-6651R-TRSize:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE) -containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP) . Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor.
Synonyms
MCI1; LRP-8; APOER2; HSZ75190; Low-density lipoprotein receptor-related protein 8; Apolipoprotein E receptor 2; LRP8
Gene ID
7804
Swiss Prot
Q14114
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
851-963/963
Target
ApoER2
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ApoER2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Specificity
This antibody will detect both the membrane bound and the secreted isoform variants of this protein.
Prediction Reactivity
Dog, Cow, Pig, Horse, Chicken, Rabbit
Gene ID URL
7804
Isotype
IgG

Related Products

CatalogName
bsm-61596R-01ApoER2 Recombinant Antibody
bsm-61596R-TRApoER2 Recombinant Antibody
bsm-61596R-RBITC-01ApoER2 Recombinant Antibody, RBITC Conjugated
bsm-61596R-PerCP-01ApoER2 Recombinant Antibody, PerCP Conjugated
bsm-61596R-PE-01ApoER2 Recombinant Antibody, PE Conjugated
bsm-61596R-PerCP-TRApoER2 Recombinant Antibody, PerCP Conjugated
bsm-61596R-HRP-TRApoER2 Recombinant Antibody, HRP Conjugated
bsm-61596R-Biotin-TRApoER2 Recombinant Antibody, Biotin Conjugated
bsm-61596R-Cy7-01ApoER2 Recombinant Antibody, Cy7 Conjugated
bsm-61596R-Cy5-01ApoER2 Recombinant Antibody, Cy5 Conjugated

Alternative Products

CatalogName
BS5615ApoER2 polyclonal antibody
TMAB-00131-01Anti-ApoER2 Polyclonal Antibody
GTR18297655-01ApoER2/LRP8 polyclonal antibody
APRab07039-01ApoER2 Rabbit Polyclonal Antibody
GTR17728513ApoER2 Rabbit Polyclonal Antibody (FITC)
GTR17719226ApoER2 Rabbit Polyclonal Antibody (HRP)
GTR17745110ApoER2 Rabbit Polyclonal Antibody (PE)
GTR17693733ApoER2/LRP8 Rabbit Polyclonal Antibody
GTR18434078ApoER2 Rabbit Polyclonal Antibody (BF750)
GTR18434077ApoER2 Rabbit Polyclonal Antibody (PerCP)

Popular Products