PI3Kδ/γ-IN-1

PI3Kδ/γ-IN-1

• CAS Number: 1980884-01-2
• UNSPSC Description: PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies.
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3kδ-γ-in-1.html
• Solubility: DMSO : ≥ 2.22 mg/mL
• Smiles: O=C1N(C)C2=CN=C(NC3=CC=CC(S(=O)(N4CCC(O)CC4)=O)=C3)N=C2N(C)C5=CC=C(C)C=C15
• Molecular Weight: 508.59
• References & Citations: [1]Ferguson FM, et al. Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors. ACS Med Chem Lett. 2016 Aug 2;7(10):908-912.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported