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Isoliquiritigenin (Standard)

CAT: 0804-HY-N0102R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0102R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isoliquiritigenin (Standard) is the analytical standard of Isoliquiritigenin. This product is intended for research and analytical applications. Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
CAS Number
961-29-5
Product Name Alternative
GU17 (Standard) ; ISL (Standard) ; Isoliquiritigen (Standard) ; SJ000286237 (Standard)
UNSPSC
12352005
Target
Aldose Reductase; Apoptosis; Autophagy; Influenza Virus; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isoliquiritigenin-standard.html
Smiles
O=C(C1=CC=C(O)C=C1O)/C=C/C2=CC=C(O)C=C2
Molecular Formula
C15H12O4
Molecular Weight
256.25
References & Citations
[1]Aida K, et al. Isoliquiritigenin: a new aldose reductase inhibitor from glycyrrhizae radix. Planta Med. 1990 Jun;56 (3) :254-8.|[2]Sato Y, et al. Isoliquiritigenin, one of the antispasmodic principles of Glycyrrhiza ularensis roots, acts in the lower part of intestine. Biol Pharm Bull. 2007 Jan;30 (1) :145-9.|[3]Zhang X. Natural antioxidant-isoliquiritigenin ameliorates contractile dysfunction of hypoxic cardiomyocytes via AMPK signaling pathway. Mediators Inflamm. 2013;2013:390890.|[4]Chen X, et al. Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling. J Mol Med (Berl) . 2012 Nov;90 (11) :1311-9.|[5]Traboulsi H, et al. The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection. Antimicrob Agents Chemother. 2015 Oct;59 (10) :6317-27.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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