Biotin Conjugated Human TRAIL Recombinant Rabbit Monoclonal Antibody [PSH08-06]

Biotin Conjugated Human TRAIL Recombinant Rabbit Monoclonal Antibody [PSH08-06]

• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Product Name Alternative: Apo 2 ligand antibody APO 2L antibody Apo-2 ligand antibody Apo-2L antibody APO2L antibody CD253 antibody CD253 antigen antibody Chemokine tumor necrosis factor ligand superfamily member 10 antibody Protein TRAIL antibody TL2 antibody TNF Related Apoptosis Inducing Ligand antibody TNF related apoptosis inducing ligand TRAIL antibody TNF-related apoptosis-inducing ligand antibody TNF10_HUMAN antibody TNFSF10 antibody TRAIL antibody Tumor necrosis factor (ligand) family member 10 antibody Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody Tumor necrosis factor ligand superfamily member 10 antibody
• Abbreviation: Tumor necrosis factor ligand superfamily member 10 Apo-2 ligand (Apo-2L) TNF-related apoptosis-inducing ligand (Protein TRAIL) CD253 TNFSF10 APO2L, TRAIL
• CAS Number: 9000-83-3
• Swiss Prot: P50591 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within Human TRAIL aa 114-281.
• Isotype: IgG
• Clone: PSH08-06
• Conjugation: Biotin-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: ELISA (Det)
• Positive Control: Recombinant Human TRAIL protein as the standard (HA210893).
• Concentration: 1 mg/mL
• Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH08-05] to Human TRAIL antibody (Capture) (HA722943) and recombinant Human TRAIL protein as the standard (HA210893). The reference range value is 16.5-4,000 pg/ml.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes