LGI3 Polyclonal Antibody

CAT: 0498-bs-11879R-TRSize: 20 µLDry Ice: NoHazardous: No
CAT#:0498-bs-11879R-TRSize:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
Synonyms
Leucine rich repeat LGI family member 3; Leucine-rich glioma inactivated protein 3; Leucine-rich glioma-inactivated protein 3; Leucine-rich repeat LGI family member 3; LGI1 like protein 4; LGI1-like protein 4; LGI3; LGI3_HUMAN; LGIL4.
Cellular Locus
Cytoplasm, Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
101-220/548
Target
LGI3
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LGI3
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Human, Dog, Sheep, Pig, Horse
Isotype
IgG

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