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LGI1 Polyclonal Antibody

CAT: 0498-bs-6719RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-6719RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity) . Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Synonyms
EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN; Leucine-rich glioma-inactivated protein 1; Epitempin-1; LGI1; UNQ775/PRO1569
Gene ID
9211
Swiss Prot
O95970
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
451-557/557
Target
LGI1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LGI1
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
9211
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Horse, Rabbit