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CD19 Antibody (Biotin)

CAT: 0013-GTR17857417Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR17857417Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody conjugated to Biotin which recognizes CD19 that amplifies the signaling cascade in B cells. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK) .CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells.Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) .
Product Name Alternative
B4, Leu-12, CVID3
UniProt
P15391
Reactivity
Human
Immunogen
Human CCL (chronic lymphocytic leukemia) cells
Target
CD19
Clonality
Monoclonal
Clone
4G7
Conjugation
Biotin
Field of Research
Immunology & Inflammation
Purification
Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
Concentration
1 mg/ml
Storage Conditions
Store at 2-8°C. Do not freeze.
Notes
For research use only.
Applications Notes
Flow cytrometry: Recommended dilution: 1 μg/ml.
Tested Applications
FC, ICC
Preservative
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Isotype
Mouse IgG1 kappa
Entrez
930

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