NVP-2

CAT: 0498-bs-83811C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-83811C-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
NVP-2 is a highly selective and potent (IC50 = 0.514 nM) inhibitor of cyclin dependent kinase 9 (CDK9) .1 It inhibited proliferation of MOLT4 cells (IC50 = 9 nM) . Treatment of cells with NVP-2 resulted in profound downregulation of core regulatory circuitry genes. It has also been shown to be a potent inhibitor of CDK10 (IC50 = 29 nM; this study gives an IC50 of 6 nM for CDK9) .2 NVP-2 acted synergistically with orlistat to inhibit acute myeloid leukemia cells (IC50s: Kasumi-1 cells 7.58 nM; U937 cells 8.99 nM) .3
Conjugation
Unconjugated
Buffer
Off-white to beige solid
Storage Conditions
-20°C

Related Products

CatalogName
bs-82993C-01NVP-231
bs-83033C-01NVP-BGJ398
bs-60419C-01NVP-TAE684
bs-83258C-01NVP-BEZ235
bs-6622C-01NVP-ACC-789
bs-60328C-01NVP-TNKS656, Wnt / Tankyrase Inhibitor
bs-66050C-01NVP-BGT226, PI3K/mTOR Dual Inhibitor
bs-75852C2-[2- (2-Aminophenoxy) ethoxy]-4-methyl-benzenamine
bs-75914C-012- (2-Benzofuranyl) -3-hydroxychromone
bs-70223RPhospholipase C β2 (PLC-β2) Antibody

Alternative Products

CatalogName
MBS133003NVP-2
6535/5NVP 2
A17022-5NVP-2 5mg
A17022-25NVP-2 25mg
A17022-100NVP-2 100mg
A17022-10NVP-2 10mg
A17022-50NVP-2 50mg
A17022-1NVP-2 1mg
A17022-2NVP-2 2mg
A17022-10mM-DNVP-2 10mM * 1mL in DMSO

Popular Products