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CU-CPT8m

CAT: 0498-bs-83724C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83724C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CU-CPT8m is a potent and selective antagonist of toll-like receptor 8 (TLR8) acting via stabilization of the TLR8 homodimer.1 It inhibits TNFα and IL-8 expression induced by the TLR8 agonist resiquimod at 1 mM and suppresses TLR8-mediated proinflammatory signaling in various cell lines, human primary cells and patient specimens. It reverses phenotypes involved in TLR8-activating fibroblasts.2 CU-CPT8m promotes erythroid cell proliferation and differentiation.3
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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