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Necrosulfonamide

CAT: 0498-bs-83418C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-83418C-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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