Necrosulfonamide

• Target:

  PI4K|||PI3K|||MLK

• Related Pathways:

  PI3K/Akt/mTOR signaling|||MAPK

• Purity:

  0.9949

• Bioactivity:

  Necrosulfonamide ((E) -Necrosulfonamide) is a necroptosis inhibitor that targets MLKL and is selective. Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosomal complex from interacting with its downstream effectors.

• Smiles:

  COc1nccnc1NS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)cc1

• Molecular Formula:

  C18H15N5O6S2

• Molecular Weight:

  461.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1360614-48-7