Necrosulfonamide

• Target :

  PI4K|||PI3K|||MLK

• Related Pathways :

  PI3K/Akt/mTOR signaling|||MAPK

• Purity :

  0.9949

• Bioactivity :

  Necrosulfonamide ((E) -Necrosulfonamide) is a necroptosis inhibitor that targets MLKL and is selective. Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosomal complex from interacting with its downstream effectors.

• Smiles :

  COc1nccnc1NS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)cc1

• Molecular Formula :

  C18H15N5O6S2

• Molecular Weight :

  461.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1360614-48-7