D (+) -Cycloserine

• Background :

  Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors1. Blocks kainate-induced seizures2 and displays anticonvulsant effects3 in rat models. Facilitates synaptic plasticity but impairs glutamatergic neurotransmission in rat hippocampal slices4. Enhances activity-dependent plasticity in human adults5.

• Conjugation :

  Unconjugated

• Buffer :

  White or off-white solid

• Storage Conditions :

  -20°C