Apicidin

• Background :

  Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC’s) .1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1α protein levels and transcriptional activity in human and mouse tumor cell lines.3

• Conjugation :

  Unconjugated

• Buffer :

  White solid

• Storage Conditions :

  -20°C