Apicidin

CAT: 0498-bs-83228C-01Size: 1 mgDry Ice: NoHazardous: No

CAT#:0498-bs-83228C-01Size:1 mg

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Background

Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC’s) .1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1α protein levels and transcriptional activity in human and mouse tumor cell lines.3

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

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