Apicidin

• CAS Number :

  183506-66-3

• Target :

  Autophagy|||Parasite|||Apoptosis|||HDAC

• Related Pathways :

  Autophagy|||Apoptosis|||Chromatin/Epigenetic|||Microbiology/Virology|||DNA Damage/DNA Repair

• Purity :

  0.9993

• Bioactivity :

  Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic and antiproliferative activity. It attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, making it a valuable tool for leukemia research.

• Smiles :

  [H][C@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@H](Cc1cn(OC)c3ccccc13)NC(=O)[C@H](CCCCCC(=O)CC)NC2=O)[C@@H](C)CC

• Molecular Formula :

  C34H49N5O6

• Molecular Weight :

  623.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C