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GW-501516

CAT: 0498-bs-83217C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83217C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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HY-10838R-01GW 501516 (Standard)
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