Chroman 1

CAT: 0498-bs-83059C-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0498-bs-83059C-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Extremely potent inhibitor of Rho kinase II (ROCK-II) 1,2 – it displayed greater selectivity and potency compared to Y-27632 (IC50’s: ROCK I = 52 pM/ROCK II = 1 pM; Y-27632 IC50’s: ROCK I = 71 nM/ROCK II = 46 nM) 3. Chroman 1, used in conjunction with trans-ISRIB (Cat# 10-1539), Emricasan (Cat# 10-4280), and polyamines (CEPT cocktail), promotes cytoprotective cell survival in human pluripotent stem cells (hPSCs) and was found to superior to Y-27632.3 Chroman 1 is an important new tool in the generation and maintenance of stem cells.

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

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Chroman 1

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