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JNK-IN-8

CAT: 0498-bs-83016C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83016C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively) .1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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