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BT2

CAT: 0498-bs-83001C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83001C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BT2 is an inhibitor of the mitochondrial branched-chain α-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 µM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 µM) of myeloid cell leukemia 1 (Mcl 1), a Bcl-2 family protein.2
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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