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KC7F2

CAT: 0498-bs-82999C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82999C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KC7F2 is an inhibitor of HIF-1α (IC50 = 20 µM) .1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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